ملخص الدراسة:

Background: Misoprostol is a new promising agent for cervical ripening and induction of labor. The ideal dose;_x000D__x000D_
route and frequency of administration of misoprostol are still under investigation._x000D__x000D_
Aims: To examine 50 μg of oral misoprostol for induction of labor for its different efficiency and safety on_x000D__x000D_
maternal& fetal outcomes._x000D__x000D_
Methods: This was a case control study for sample size of 300 women 152 as group and 148 as control. The_x000D__x000D_
participants were chosen from the labor room at Al Shifa Hospital the largest hospital in Gaza Strip & the first_x000D__x000D_
governmental hospital which started to use oral misoprostol for labor induction beside the routine use of_x000D__x000D_
prostaglandin E2. The study was conducted between September 2018, and December 2018. All the group were_x000D__x000D_
assigned to receive misoprostol 50 μg orally every 6 h for a maximum of 4 doses._x000D__x000D_
Results: The current study revealed that total h for the oral misoprostol induction group 20.5 h compared to 5.7 h_x000D__x000D_
in the control group. The Maternal complication in oral misoprostol was 12.5% versus 2.7% in the control group._x000D__x000D_
Moreover, oral misoprostol group has a higher rate in birth canal injury & caesarean section 9.2%, 19.1% versus_x000D__x000D_
2.0%, 0.7% respectively with control. The result revealed that, overall fetal complication was a higher rate in_x000D__x000D_
misoprostol group 14.5% versus 7.3% in control._x000D__x000D_
Conclusion: it was found that misoprostol induction method still has a higher maternal & fetal complication which_x000D__x000D_
required more investigation before being recommended as an alternative method in labor induction

توثيق المرجعي (APA)